ultimately we have no meaning, this is what nihilists such as myself believe. Because we sentient beings fear death we are prone to theistic delusions and cling to desperate concepts such as the afterlife and reincarnation. Life is roller-coaster and you've only got one ride; why finish your ride so soon? I found meaning in other people, just as you have with your mother and your sister. Committing suicide is one of the dumbest things a person could do (unless you are in some extreme circumstance which you aren't.)
Find you meaning in life, what makes you feel accomplished? How does this accomplishment relate to a profession?
Perhaps its time for you to go back to school and further your education. I don't know your specific circumstance, but improving one's self understanding is always a good start.
Good luck